Program | 2023 Midwest Clinical and Translational Research Meeting of CSCTR and MWAFMR

Monday
April 24, 2023

Tuesday
April 25, 2023

Monday, April 24, 2023		Meeting Room
7:00 am – 5:00 pm	Registration	Regency Ballroom Foyer (second floor)
7:00 am – Noon	Poster setup	Regency Ballroom A/B (second floor)
8:15 am – 8:30 am	Welcome and Opening Remarks Suthat Liangpunsakul, MD, MPH CSCTR President Jennifer Alexander-Brett, MD, PhD Chair, AFMR Midwestern Section	Regency Ballroom C/D/E (second floor)
8:30 am – 10:30 am	MWAFMR Career Development Workshop Moderator: Jeffrey Salomon, MD Pediatric Critical Care Physician, University of Nebraska Medical Center Speakers: Managing Clinical Responsibilities and Developing Translational Research Projects Jesse Davidson, MD, MPH, MS Associate Medical Director, Children's Hospital Colorado Research Institute/Associate Professor, Pediatrics Components of a Mentee Development Plan Ajay K. Jain, MD Pediatric Gastroenterologist at Cardinal Glennon Children's Medical Center/Medical Director of Pediatric Liver Transplantation at Saint Louis University VA Aspects of Career Development Frederick G. Hamel, PhD Associate Chief of Staff for Research, VA Nebraska-Western Iowa Health Care System, and Professor, University of Nebraska Medical Center	Regency Ballroom C/D/E (second floor)
10:30 am – 10:45 am	Coffee Break	Regency Ballroom Foyer (second floor)
10:45 am – 12:30 pm	New Investigator Session Moderator: Suthat Liangpunsakul, MD, MPH Professor of Medicine, Indiana University School of Medicine Presenters: Outstanding Young Investigator ALDH2 Deficiency Exacerbates Binge Alcohol-Induced Gut Leakiness, Endotoxemia, And Acute Liver Injury Through The Gut-Liver Axis Wiramon Rungratanawanich, PhD, National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH AFMR Henry Christian Awardee Process Evaluation Of The Community Asthma Program On The Navajo Nation Using The Re-Aim Framework Priyanka Ravi, MDS, Asthma & Airway Disease Research Center, Mel & Enid Zuckerman College of Public Health, University of Arizona 2022 Early Career Development Awardees *Mucosal Bacteria are Associated with Altered Intestinal Premeability in Cirrhosis and Vary form duodenum to Colon* Patricia Bloom, MD, University of Michigan Autophagy In Peripheral Artery Disease: Clinical Significance and Therapeutic Potential Shuai Li, MD, PhD, University of Nebraska Medical Center Regulation Of Transthyretin Expression in Pancreatic Islet Alpha Cell Function Rachel Reinert, MD, PhD, University of Michigan Effects Of Asthma- And Allergic Disease-Risk Genetic Variants on Lung Resident Immune Cells' Responses Nathan Schoettler, MD, PhD, University of Chicago Role of the Long Non-Coding RNA H19 In Alcoholic Liver Disease Zhihong(Joe) Yang, PhD, Indiana University School of Medicine	Regency Ballroom C/D/E (second floor)
12:30 pm – 1:30 pm	Lunch	Regency Ballroom A/B (second floor)
1:30 pm – 2:30 pm	Department Chair Session Moderator: Suthat Liangpunsakul, MD, MPH Professor of Medicine, Indiana University School of Medicine Session Chair: Michelle Kang Kim, MD, PhD Chair of the Department of Gastroenterology, Hepatology and Nutrition with Cleveland Clinic’s Digestive Disease & Surgery Institute Junior Investigators: Hierarchical organization of cellular responses on quantitative multiomics identifies mechanisms of sarcopenia in alcohol related liver disease Nicole Welch, MD Assistant Professor, Cleveland Clinic Non-Biopsy Diagnosis of Adult Celiac Disease in the United States Claire Jansson-Knodell, MD Associate Staff, Gastroenterology, Hepatology, and Nutrition with Cleveland Clinic's Digestive Disease & Surgery Institute Cohort for Healing Arthritis, Skin, and Eye Extra-Intestinal Manifestations (CHASE-EIM) Katherine A. Falloon, MD Inflammatory Bowel Disease Fellow, Cleveland Clinic	Regency Ballroom C/D/E (second floor)
2:30 pm – 2:45 pm	Break
2:45 pm – 3:45 pm	Cardiology/Pulmonary Lecture Moderator: Steven Dudek, MD Professor of Medicine, University Illinois at Chicago Speaker: Use of imaging to evaluate lung disease in airways disease and COVID Mario Castro, MD, MPH Professor of Medicine, Vice Chair for Clinical and Translational Research, Department of Medicine, Chief, Division of Pulmonary, Critical Care and Sleep Medicine at University of Kansas Medical Center	Regency Ballroom C/D/E (second floor)
3:45 pm – 5:00 pm	Poster Session and Opening Reception	Regency Ballroom A/B (second floor)
5:00 pm – 5:10 pm	Break
5:10 pm – 6:10 pm	Max Miller Lecture in Diabetes Research Moderators: Dawn Belt Davis, MD, PhD Professor University of Wisconsin – Madison Terry G. Unterman, MD Professor of Medicine, Physiology and Biophysics, University of Illinois at Chicago Speakers: *The ailing beta cell in Type 1 diabetes: Insights from a trip to the ER* Carmella Evans-Molina, MD, PhD, MS Director, IU Center for Diabetes and Metabolic Diseases (CDMD) Diabetes Program Director, Herman B Wells Center for Pediatric Research Director of the Indiana Diabetes Research Center Islet and Physiology Core, Eli Lilly and Company Professor of Pediatric Diabetes Sexual dimorphism in metabolism: Estrogens in the brain Pingwen Xu, PhD Assistant Professor, Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois Chicago College of Medicine	Burnham B/C (second floor)
5:10 pm – 6:10 pm	Inflammation, Immunity, and Transplant Moderators: Nadim Mahmud, MD, PhD Professor, Hematology/Oncology, Department of Medicine, University of Illinois College of Medicine, Chicago Director, Clinical Stem Cell Laboratory, Blood and Marrow Transplant Program Suman Setty, PhD, MBBS Associate Professor, Department of Department of Pathology, University of Illinois at Chicago College of Medicine Speakers: Putting the Me Back in Medicine: Opportunities to Personalize Care in Kidney Transplant Recipients Roslyn B. Mannon, MD Vice Chair of Research, Department of Internal Medicine/Professor, Division of Nephrology/Nephrology Associate Chief of Research Achieving Solid Organ Transplant Tolerance Through Therapeutic Cell Transfer: Where Do We Stand? Joseph R. Leventhal, MD, PhD Fowler McCormick Professor of Surgery/Professor of Surgery (Organ Transplantation), Northwestern Medicine, Feinberg School of Medicine	Regency Ballroom C/D/E (second floor)
6:15 pm	Dinner (on your own)
Tuesday, April 25, 2023		Meeting Room
7:00 am – 2:30 pm	Registration	Regency Ballroom Foyer (second floor)
7:30 am – 9:00 am	Mentor Breakfasts How to learn from and land leadership positions on Regional and National committees Mentors: Sidharth Mahapatra, MD, PhD; Anupam Kotwal, MD Becoming an independent investigator: Asking the right questions and funding your research Mentors: Suthat Liangpunsakul, MD, MPH; Roslyn B. Mannon, MD; Nathan Schoettler, MD, PhD Navigating authorship: Tips from behind the scenes of a journal Mentors: Jerry Krishnan, MD, PhD; John Dickinson, MD, PhD; Shuai Li, MD, PhD Setting priorities: Communication and negotiation Mentors: Megha Ramaswamy, PhD, MPH; Jeffery Salomon, MD, MBA; Hugh Musick Identifying mentors and maintaining good mentor/mentee relationships Mentors: David Kennedy, PhD; Lynn Gerald, PhD, MSPH; Zhihong (Joe) Yang, PhD The balancing act for women in medicine and science Mentors: Jennifer Alexander-Brett MD, PhD; Michelle Kang Kim, MD, PhD; Patricia Bloom, MD The 7 Habits of Highly Effective Leaders in Science and Medicine Mentors: Steven Dudek, MD; Mario Castro, MD, MPH; Rachel Reinert, MD, PhD Crisis Management: The Pandemic and Beyond, turning challenges into opportunities for growth Mentors: Robin Mermelstein, PhD; Kevin Regner, MD; Jesse Davidson, MD	Regency Ballroom A/B (second floor)
7:30 am – 9:00 am	Attendee Breakfast	Regency Ballroom A/B (second floor)
9:00 am – 9:15 am	Break
9:15 am – 10:15 am	AFMR Keynote Presentation Moderator: Jennifer Alexander-Brett, MD, PhD Assistant Professor of Medicine, Washington University School of Medicine in St. Louis Speaker: Predicting Outcomes in Neuroendocrine Tumors Michelle Kang Kim, MD, PhD Chair of the Department of Gastroenterology, Hepatology and Nutrition with Cleveland Clinic’s Digestive Disease & Surgery Institute	Regency Ballroom C/D/E (second floor)
10:15 am – 10:30 am	Break
10:30 am – 11:30 am	Diversity, Equity, and Inclusion (DEI) Symposium Moderator: Anupam Kotwal, MD Assistant Professor, Division of Diabetes, Endocrinology & Metabolism, University of Nebraska Medical Center Speakers: Diet, Socio-environmental Stress and Colorectal Cancer Health Inequities in Chicago Lisa Tussings-Humphreys, PhD, MS, RD Associate Professor/Kinesiology and Nutrition/College of Applied Health Sciences University of Illinois Cancer Center Cardiovascular Disease and Promoting Health Equity in Asian Americans Nilay Shah, MD, MPH Assistant Professor of Cardiology and Preventive Medicine, and general and preventive cardiologist in the Bluhm Cardiovascular Institute, at Northwestern University Feinberg School of Medicine	Regency Ballroom C/D/E (second floor)
11:30 am – 12:30 pm	Lunch	Regency Ballroom A/B (second floor)
12:45 pm – 1:00 pm	Awards	Regency Ballroom C/D/E (second floor)
1:00 pm – 2:00 pm	CSCTR John B. Hickam Endowed Lecture The John B. Hickam Endowed Lectureship was established in 1981 to honor John Hickam, President of CSCR in 1970. At the time of his death in 1970, Dr. Hickam was Chair of Medicine at Indiana University School of Medicine. Dr. Hickam was internationally recognized in medical research, particularly in the areas of lung, heart and circulatory system diseases. Dr. Hickam was also responsible for the administration of research programs, which established the Indiana University School of Medicine as one of the nation’s primary centers for research in heart disease. Moderator: Jerry A. Krishnan, MD, PhD Associate Vice Chancellor for Population Health Sciences, University of Illinois at Chicago Speaker: De-mystifying implementation science: A pragmatic guide Russell Glasgow, PhD Research Professor, Department of Family Medicine University of Colorado/Director, ACCORDS Dissemination and Implementation Science (D&I) Program	Regency Ballroom C/D/E (second floor)
2:00 pm – 2:15 pm	Coffee Break	Regency Ballroom Foyer (second floor)
2:15 pm – 3:15 pm	Implementation Science Workshop Russell Glasgow, PhD Research Professor, Department of Family Medicine University of Colorado/Director, ACCORDS Dissemination and Implementation Science (D&I) Program Mario Castro, MD, MPH Professor of Medicine, Vice Chair for Clinical and Translational Research, Department of Medicine, and Chief, Division of Pulmonary, Critical Care and Sleep Medicine at University of Kansas Medical Center Robin Mermelstein, PhD Distinguished Professor of Psychology, Director, Institute for Health Research and Policy, and Assistant Dean, College of Medicine, University of Illinois Chicago	Regency Ballroom C/D/E (second floor)
3:15 pm – 3:30 pm	Break
3:30 pm – 4:45 pm	Translational Science I: Implementation Science Poster Discussion Moderators: Lynn Gerald, PhD, MSPH Assistant Vice Chancellor, Population Health Sciences Program, University of Illinois Chicago Megha Ramaswamy, PhD, MPH Professor, Population Health, University of Kansas School of Medicine A Hybrid 2 Trial Of Phat Life Effectiveness And Implementation For Adolescents On Probation: Delivery By Youth Leaders Vs. Probation Staff Geri Donenberg, PhD University of Illinois Chicago Helping Studies Fit People: Using Human-Centered Design Methods To Bridge The Implementation Gap In Clinical Trials Jennifer Sculley, MDes University of Illinois Chicago My ILLINet Recover Return Of Individual Research Results (Mirror): A Pilot Study About Participant Preferences In A Longitudinal COVID Study Denise A. Kent, PhD, RN, APN University of Illinois Chicago COVID-19 Intervention Implementation: Disruptions And Barriers For Elementary Classroom Teachers, School Health Staff, And School Cleaning Staff Amanda M. Wilson, PhD University of Arizona Using Implementation Science To Inform The Preparation Phase Of The Multiphase Optimization Strategy (MOST) Framework Katherine G. Merrill, PhD University of Illinois Chicago Patient And Provider Perceived Barriers And Facilitators To Ophthalmology Visit Adherence: Identifying The Role Of Motivation Versus Ability Archit V. Potharazu, BE University of Illinois Chicago Introducing A Real-Time Method For Identifying The Predictors Of Non-Compliance With Event-Based Reporting Of Tobacco Use In Ecological Momentary Assessment Ashley D. Kendall, PhD University of Illinois Chicago	Regency Ballroom B (second floor)
3:30 pm – 4:45 pm	Translational Science Oral Session II: Cardiac, Renal, Endocrine/Metabolism, Gastroenterology, and Health Outcomes Moderator: Suthat Liangpunsakul, MD, MPH Professor of Medicine, Indiana University School of Medicine *An Improved Model Of Chronic Kidney Disease: Adenine Diet In The SKH1 Mouse* Benjamin W. French The University of Toledo *Melatonin Treatment Protects Against Thioacetamide (TAA)-Mediated Liver Fibrosis By Selectively Activating Sirt1 Deacetylase And Protein Deacetylation* Wiramon Rungratanawanich, PhD National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH A Lipidomics Approach To Predicting Pulmonary Hypertension In Human Heart Failure With Preserved Ejection Fraction Vaishnavi Aradhyula, MS University of Toledo College of Medicine and Life Sciences Right Ventricular Function On Cardiovascular Magnetic Resonance Imaging And Long-Term Outcomes In Stable Heart Transplant Recipients Collin M. Barrett, BA University of Minnesota Medical School Longitudinal Characterization Of Metabolic Changes In ADPKD Cassandra J. Trask Mayo Clinic PKD Center Aryl Hydrocarbon Receptor Activation Protects Against Pregnancy Induced Insulin Resistance Medha Priyadarshini, PhD University of Illinois at Chicago *Phosphorylation Of Mitochondrial Calcium Uniporter In Heart Failure* Madeline Kelly University of Minnesota	Regency Ballroom C/D/E (second floor)
3:30 pm – 4:45 pm	Translational Science Oral Session III: Pulmonary/Critical Care, Hematology/Oncology, Rheumatology/Immunology and Neurology Moderator: Steven Dudek, MD Professor of Medicine, University Illinois at Chicago *Clinical Research Participant As Customer: Five Principles For Designing Human-Centered Research Studies* R. McKinley Sherrod, MDes University of Illinois at Chicago Inducing Iron Imbalance By Targeting The ABCB7/GPX4 Axis Accelerates Ferroptosis In Medulloblastoma Ranjana K. Kanchan, PhD University of Nebraska Medical Center RIG-I Agonist SLR10 Promotes Macrophage M1 Polarization During Influenza Virus Infection Jordan P. Metcalf, MD University of Oklahoma Health Sciences Center GATA2 Suppresses Chromosomal Instability And Is Predictive Of Survival In Endometrial Serous Carcinoma Apoorva Tarihalkar Patil, MS University of Wisconsin School of Medicine and Public Health Distinct Transcriptional Programs Define Immunotype Specific CD4+ T-Cell Subtypes In Sarcoidosis Christian Ascoli, MD University of Illinois at Chicago Transcriptome Based Drug Repurposing In Group 3 Medulloblastoma David J. Doss Creighton University Murine Model Of Phenylhydrazine-Induced Chronic Hemolysis Combined With Hypoxia Leads To Development Of Severe Pulmonary Hypertension Janae Gonzales, MD University of Illinois at Chicago	Burnham BC (second floor)
4:45 pm – 5:45 pm	Closing Reception	Regency Ballroom Foyer (second floor)

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Monday, April 24, 2023

Meeting Room

Registration

Poster setup

Welcome and Opening Remarks

MWAFMR Career Development Workshop

New Investigator Session

Presenters:

Outstanding Young Investigator

AFMR Henry Christian Awardee

2022 Early Career Development Awardees

Lunch

Department Chair Session

Junior Investigators:

Break

Cardiology/Pulmonary Lecture

Poster Session and Opening Reception

Break

Max Miller Lecture in Diabetes Research

Inflammation, Immunity, and Transplant

Dinner (on your own)

Tuesday, April 25, 2023

Meeting Room

Registration

Mentor Breakfasts

Attendee Breakfast

Break

AFMR Keynote Presentation

Break

Diversity, Equity, and Inclusion (DEI) Symposium

Lunch

Awards

CSCTR John B. Hickam Endowed Lecture

Coffee Break

Implementation Science Workshop

Break

Translational Science I: Implementation Science Poster Discussion

Translational Science Oral Session II: Cardiac, Renal, Endocrine/Metabolism, Gastroenterology, and Health Outcomes

Translational Science Oral Session III: Pulmonary/Critical Care, Hematology/Oncology, Rheumatology/Immunology and Neurology

Closing Reception

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