2020 Midwest Clinical & Translational Research Meeting

Schedule

Thursday, April 2

9 am – 7 pm

Registration

11 am – 3 pm

CSCTR Council Meeting

1 – 3 pm

MWAFMR Career Development Workshop
Moderators: Joumana T. Chaiban, MD, FACE, University of Illinois at Chicago/Advocate Christ Medical Center; Edgar V. Lerma, MD, FACP, FASN, University of Illinois at Chicago; Konstantinos Voudris, MD, PhD, Rush University in Chicago

Scientists on Social Media: Claiming the Digital Space
Armand Krikorian, MD, University of Illinois at Chicago/ Advocate Christ Medical Center

Writing in the Sciences
Kristin Sainani, PhD, Stanford University

Journal of Investigative Medicine (JIM) Editor-in-Chief
Richard W. McCallum, MD, Texas Tech University Health Sciences Center El Paso

3:15 – 3:30 pm

Welcome

3:30 – 5 pm

New Investigator Session
Moderators: Joumana T. Chaiban, MD, FACE, University of Illinois at Chicago/Advocate Christ Medical Center; David J. Kennedy, PhD, The University of Toledo; Jeffrey Laurence, MD, Weill Cornell Medical College; Gregory M. Vercellotti, MD, FACP, University of Minnesota

AFMR Henry Christian Awardees
TORTURE BY A TORTUOUS ARTERY: A RARE CASE OF FIBROMUSCULAR DYSPLASIA IN A YOUNG MALE COMPLICATED BY ACUTE RENAL INFARCTION
Munis Mahboob Ahmed, St Mary Mercy Hospital, Livonia

ABO, A SMALL MOLECULE INHIBITOR OF INTEGRIN BETA4, ATTENUATES ACUTE LUNG INJURY IN MURINE MODELS
Weiguo Chen, MD, PhD, University of Illinois at Chicago

AFMR Junior Physician-Investigator Awardee
A POLYMORPHISM IN THE UGT1A9 GENE IS ASSOCIATED WITH NEUTROPENIA IN LUNG TRANSPLANT RECIPIENTS RECEIVING MYCOPHENOLIC ACID FOR IMMUNOSUPPRESSION
Laneshia K. Tague, Washington University in St. Louis

MWAFMR Trainee Travel Awardees
STREPTOCOCCUS PNEUMONIAE ACTIVATION OF NATURAL KILLER CELL IL-10 IN THE LUNG
Sarah E. Clark, PhD, University of Colorado Denver

MICRO PARTICLE IMAGE VELOCIMETRY FOR IN VITRO ASSESSMENT OF PATIENT SPECIFIC WHOLE BLOOD RHEOLOGY
Erdem Kucukal, Case Western Reserve University

AUTOPHAGY REGULATES MUC5AC DEGRADATION DURING RESOLUTION OF MUCOUS CELL METAPLASIA IN AIRWAY DISEASE
John D. Dickinson, MD, PhD, University of Nebraska Medical Center
SEX AND STRAIN DETERMINE THE METABOLIC RESPONSE TO DIETARY PROTEIN LEVEL
Cara L. Green, PhD, University of Wisconsin-Madison

Outstanding Young Investigator
EMC10, A NOVEL CIRCULATING FACTOR, PROMOTES DIET-INDUCED OBESITY VIA SUPPRESSION OF ADIPOCYTE THERMOGENESIS
Yanliang Li, PhD, University of Illinois at Chicago

Featured New Investigator
Abnormalities in Proinsulin Processing in Islets from Individuals with Longstanding T1D
Emily K. Sims MD, Indiana University School of Medicine

Early Career Development Awardees
SENSITIVITY IS RELATED TO INCREASED SKELETAL MUSCLE MITOCHONDRIAL RESPIRATORY CAPACITY DURING INSUFFICIENT SLEEP
Josiane L. Broussard, PhD, Colorado State University

SUSPECTED DYSPHAGIA IN COMMUNITY-DWELLING OLDER ADULTS RECEIVING MEAL SUPPORT
Nicole Rogus-Pulia, PhD, University of Wisconsin-Madison

5 – 6:30 pm

Poster Session A & Opening Reception

6:30 – 8 pm

Cardiology / Pulmonary Lecture
Moderator: Steven Dudek, MD, University Illinois at Chicago

Single Cell Analysis of Lung Populations in Pulmonary Fibrosis
Paul Reyfman, MD, MS, Instructor of Medicine, Northwestern University Feinberg School of Medicine

Airway and Extrapulmonary Effects of Eosinophil Inflammation
Nizar N. Jarjour, MD, Professor of Medicine, University of Wisconsin School of Medicine

Max Miller Lecture in Diabetes Research
Moderators: Dawn Belt Davis, MD, PhD, University of Wisconsin – Madison; Terry G. Unterman, MD, University of Illinois at Chicago VA West Side Medical Center

Endocrine Regulation of Carbohydrate Homeostasis by FGF21
Matthew J. Potthoff, PhD, Associate Professor, University of Iowa

Modulating Thermogenic Beige Fat for Metabolic Health
Yuwei Jiang, PhD, Assistant Professor, University of Illinois at Chicago

Mapping Mitochondrial Nutrient Metabolism in Liver
Shawn C. Burgess, PhD, Professor, Center for Human Nutrition and Department of Pharmacology, UT Southwestern Medical Center

Renal / Transplant Lecture
Moderator: Suman Setty, MBBS, PhD, University of Illinois at Chicago

Does the Microbiome Predict Kidney Disease or does it Influence it?
Sanjeev Akkina, MD, Loyola University Medical Center

Biomarkers in Nephrology
Jay L. Koyner, MD, University of Chicago

Transplant Biomarker Development
Bruce Kaplan, MD, University of Arizona College of Medicine

7 – 9 pm

Social Event with American Physician Scientists Association

Friday, April 3

7 am – 3:30 pm

Registration

7 – 8 am

Mentor Breakfast
How to Learn from and Land Leadership Positions on Regional and National Committees; TBD
Sticking up for Yourself: Communication and Negotiation; Suthat Liangpunsakul, MD
Asking the Right Questions as you Develop your Research Program; TBD
Becoming an Independent Investigator: How do I Separate Myself from my Mentor(s) and Start my own Laboratory?; John Dickinson, MD, PhD
Navigating Authorship: Tips from Behind the Scenes of a Journal; Jeffrey Laurence, MD and Luke Verillo
Funding your Research: Writing Successful Grant Applications; TBD
Setting Priorities: When to Say Yes and How to Say No; Debra J. Romberger, MD
Identifying Mentors and Maintaining Good Mentor/Mentee Relationships; TBD
The Balancing act for Women in Medicine and Science; Attaya Suvannasankha, MD
Innovation and Commercialization in Medicine and Science: Creating and Positioning your Intellectual Property at the Service of Others; Scott E. Parazynski, MD
Creating Captivating Presentations to Communicate Your Science; Jacquelyn Kulinski, MD
The 7 Habits of Highly Effective Leaders in Science and Medicine; TBD

 

CSCTR Membership Application Processing

7:30 – 8:30 am

Attendee Breakfast

8:15 – 8:30 am

CSCTR Annual Business Meeting

8:30 – 9:30 am

AFMR Keynote Presentation
Moderator: Joumana T. Chaiban, MD, FACE, University of Illinois at Chicago/Advocate Christ Medical Center

Academia Collaborations with Industry – Lessons for the Future
S. Sethu Reddy, MD, Central Michigan University

9:30 – 10:30 am

Department Chair Session
Chair: Michael S. Bronze, MD, MACP, FIDSA, FRCP, University of Oklahoma Health Sciences Center

Title TBA
Matthew Walters, PhD, Division of Pulmonary, Critical Care and Sleep Medicine

Title TBA
Parthasarathy Chandrakesan, PhD, Assistant Professor of Research

Studies of the Microbiome in Osteoarthritis
Matlock A Jeffries, MD, Assistant Professor of Medicine, Rheumatology

10:30 am – 12 pm

BMT Symposium
Harnessing the Immune System against Cancer: Lessons from Bone Marrow Transplant

Moderators: Pavan Reddy, MD, University of Michigan Cancer Center; Gregory M. Vercellotti, MD, FACP, University of Minnesota

Immune Cellular Therapy for Malignancy: TILS CAR T-Cells
Michael R. Bishop, MD, University of Chicago

Why does Thrombotic Microangiopathy Occur after Stem Cell Transplant?
Stella M Davies, MBBS, PhD; Cincinnati Children's Hospital Medical Center

Lessons from the Biology of Pregnancy Applied to Graft-Versus-Host Disease
Shernan Holtan, MD, University of Minnesota

12 – 1:30 pm

Poster Session B & Lunch

Annual Translational Research Editorial Meeting

1:45 – 2:45 pm

CSCTR John B. Hickam Endowed Lecture
The John B. Hickam Endowed Lectureship was established in 1981 to honor John Hickam, President of CSCR in 1970.  At the time of his death in 1970, Dr. Hickam was Chair of Medicine at Indiana University School of Medicine.  Dr. Hickam was internationally recognized in medical research, particularly in the areas of lung, heart and circulatory system diseases.  Dr. Hickam was also responsible for the administration of research programs, which established the Indiana University School of Medicine as one of the nation’s primary centers for research in heart disease.
Moderator: David Kennedy, PhD, University of Toledo  


Innovation in the Extreme
Scott E. Parazynski, MD, physician and former NASA astronaut

2:45 – 3:30 pm

Research Innovations
Moderator: John D Dickinson, MD, PhD

Challenges of Conducting Research on rare viral illness such as Ebola
James Lawler, MD, MPH, University of Nebraska Medical Center

3:45 – 4:45 pm

Translational Science I: Cardiac, Renal, Endocrine, and Metabolic Diseases
Moderator: Mohammad N. Uddin, PhD, FAHA

OBESITY-ASSOCIATED HYPOXIA CONTRIBUTES TO ABERRANT METHYLATION OF GENES IMPLICATED IN INFLAMMATION AND VASCULAR FUNCTION
Abeer M. Mahmoud, MD, PhD, University of Illinois at Chicago

SIRTUIN-3 MEDIATES SEX DIFFERENCES IN ISCHEMIA-REPERFUSION AND AGING-RELATED KIDNEY INJURY
Jenny S. Pan, MD, Baylor College of Medicine

ABCC9 IS NECESSARY FOR NORMAL CARDIAC MITOCHONDRIA STRUCTURE AND FUNCTION
Gregory Aubert, MD, PhD, Loyola University Stritch School of Medicine

FASTING, NOT REDUCED CALORIC INTAKE, MEDIATES THE EFFECTS OF A CALORIE RESTRICTED DIET ON SYSTEMIC INSULIN SENSITIVITY AND THE LIVER METABOLOME AND EPIGENOME
Heidi H. Pak, University of Wisconsin-Madison

KIDNEY FIBROSIS IS MITIGATED BY A DUAL ACTING FARNESOID X RECEPTOR AGONIST AND SOLUBLE EPOXIDE HYDROLASE INHIBITOR IN A MOUSE MODEL
Md Abdul Hye Khan, PhD, Medical College of Wisconsin

Early Career Development Awardee
CONTRIBUTION OF HEPATOCYTE-SPECIFIC PPAR GAMMA TO THE DEVELOPMENT OF NON-ALCOHOLIC STEATOHEPATITIS (NASH), INSULIN RESISTANCE AND OBESITY
Jose Cordoba Chacon, PhD, University of Illinois at Chicago

Translational Science II: Pulmonary, Critical Care, Infectious Disease, Hematology, Oncology, and Neurology
Moderator: Pavan Reddy, MD

GENETIC STRATEGIES TO TREAT VISION LOSS IN A MURINE MODEL OF USHER SYNDROME TYPE 1C
Katelyn N. Robillard, Louisiana State University Health Sciences Center

RECRUITMENT OF BONE MARROW DERIVED MONOCYTES INTO INFLAMED LUNGS IN HYPOXIC PULMONARY HYPERTENSION
Rahul Kumar, PhD, University of California San Francisco

Early Career Development Awardee
UTILIZING IN VITRO MODELS OF INTRAVENTRICULAR HEMORRHAGE OF PREMATURITY TO SCREEN ANTI-INFLAMMATORY AND WHITE MATTER PROTECTIVE COMPOUNDS
Brandon A. Miller, MD, PhD, University of Kentucky

MRSA-INDUCED ENDOTHELIAL INJURY AND LUNG INJURY ARE REVERSED BY FTY720 S-PHOSPHONATE
Lichun Wang, PhD, University of Illinois at Chicago

ADMISSION NASAL EPITHELIAL GENE EXPRESSION PREDICTS DURATION OF ILLNESS IN CHILDREN WITH CRITICAL BRONCHIOLITIS
Bria Coates, MD, Northwestern University

UBIQUITIN E3 LIGASE NEDD4L SUPPRESSION PROMOTES LUNG FIBROBLAST DIFFERENTIATION AND EXTRACELLULAR MATRIX ACCUMULATION
Qinmao Ye, MS, The Ohio State University College of Medicine

Clinical Science: Case Reports, Health Outcomes, and Epidemiology
Moderator: Jerry A. Krishnan, MD, PhD

WHEN AFIB GOES BAD...THE DANGERS OF ATRIAL FIBRILLATION ABLATIONS
Ali Hasnie, MD, CMQ, University of Toledo

PREOPERATIVE GOAL-SETTING BY PATIENTS IS CORRELATED WITH BASELINE AND NOT 6-WEEK OUTCOMES FOLLOWING TOTAL KNEE ARTHROPLASTY (TKA)
Vesta Nwankwo, BS, Duke University School of Medicine

MASSIVE PROTEINURIA IN A YOUNG MALE WITH A DIFFUSE RASH
Ayham Alagha, MD, West Suburban Medical Center

PROSPECTIVE EFFECTS OF A GROUP-BASED MOTHER-DAUGHTER INTERVENTION FOR AFRICAN AMERICAN ADOLESCENT GIRLS ON MENTAL HEALTH SYMPTOMS AND SEXUALLY TRANSMITTED INFECTIONS
Ashley Kendall, PhD, University of Illinois at Chicago

DESCRIBING AND ASSESSING A NEW METHOD OF APPROXIMATING INDIVIDUAL-LEVEL INCOME IN CANCER REGISTRIES
Uriel Kim, BS, Case Western Reserve University

BARRIERS TO FITBIT USE AMONG LOW-INCOME MINORITY WOMEN WITH ASTHMA
Darshil Patel, University of Illinois at Chicago